Article
IL-20, IL-21 and p40: potential biomarkers of treatment response for ustekinumab.
Acta dermato-venereologica - 27 Mar 2013
Gedebjerg Anne, Johansen Claus, Kragballe Knud, Iversen Lars
Abstract excerpt
Although biological drugs in psoriasis treatment show clinical efficacy, there are still a proportion of patients in whom little treatment response is obtained. The aim of this study was to identify molecular biomarkers for treatment response and to investigate the molecular effects of ustekinumab treatment of psoriasis. The mRNA expression of various genes in skin biopsies was analysed by quantitative polymerase...
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