Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Active chronic sarcoidosis is characterized by increased transitional blood B cells, increased IL-10-producing regulatory B cells and high BAFF levels.

PloS one - 1 Jan 2012

Saussine Anne, Tazi Abdellatif, Feuillet Séverine, Rybojad Michel, Juillard Caroline, Bergeron Anne, Dessirier Valérie, Bouhidel Fatiha, Janin Anne, Bensussan Armand, Bagot Martine, Bouaziz Jean-David

Abstract excerpt

BACKGROUND: Sarcoidosis is a multisystemic disease of unknown etiology characterized by a disproportionate Th1 granulomatous immune response in the organs involved. Plasmatic hypergammaglobulinemia and B cell accumulation in granulomatous lesions suggest the possible role of humoral immune respon...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Cell Activating Factor
Share to Cell Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chronic Disease

Share to Granuloma

Share to Hypergammaglobulinemia

Share to Interleukin-10

Share to Sarcoidosis

Share to Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 22927996
DOI: 10.1371/journal.pone.0043588
PMCID: PMC3425471

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22927996-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Active chronic sarcoidosis is characterized by increased transitional blood B cells, increased IL-10-producing regulatory B cells and high BAFF levels.PMID 22927996Read ↗

Circulating T cells in sarcoidosis have an aberrantly activated phenotype that correlates with disease outcome.Semantic proximity Read ↗

Key Players and Biomarkers of the Adaptive Immune System in the Pathogenesis of SarcoidosisSemantic proximity Read ↗

The Role of Diverse Immune Cells in Sarcoidosis.Semantic proximity Read ↗

Imbalanced distribution of regulatory T cells and Th17.1 cells in the peripheral blood and BALF of sarcoidosis patients: relationship to disease activity and the fibrotic radiographic phenotype.Semantic proximity Read ↗

Immunology of sarcoidosis: old companions, new relationshipsSemantic proximity Read ↗

Circulating cytokines in sarcoidosis: phenotype-specific alterations for fibrotic and non-fibrotic pulmonary disease.Semantic proximity Read ↗

Expansion of circulating gamma delta T cells in active sarcoidosis closely correlates with defects in cellular immunity.Semantic proximity Read ↗

Expanded lung T-bet+RORγT+ CD4+ T-cells in sarcoidosis patients with a favourable disease phenotype.Semantic proximity Read ↗

Increased expression of B cell activation factor supports the abnormal expansion of transitional B cells in systemic lupus erythematosus.Semantic proximity Read ↗

Treatment of sarcoidosis.Semantic proximity Read ↗

Characterization of natural killer and T cells in bronchoalveolar lavage and peripheral blood of sarcoidosis patients.Semantic proximity Read ↗

Bronchoalveolar lavage fluid IFN-γ+ Th17 cells and regulatory T cells in pulmonary sarcoidosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.