Article
The helicase activity of DDX56 is required for its role in assembly of infectious West Nile virus particles.
Virology - 10 Nov 2012
Xu Zaikun, Hobman Tom C
Abstract excerpt
Although flaviviruses encode their own helicases, evidence suggests that cellular helicases are also required for replication and/or assembly of these viruses. By and large, the mechanisms of action for viral and cellular helicases are not known. Moreover, in some cases, enzymatic activity is not even required for their roles in virus biology. Recently, we showed that expression of the host nucleolar helicase...
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