Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Lasting Legacy of Social Stress on the Epigenome of the Hypothalamic–Pituitary–Adrenal Axis

1 Aug 2012

Abstract excerpt

Social stress is a major factor contributing to early-life adversity that has taken on an epidemic scale. Early social stress leads to long-lasting changes in behavior, cognition, mood and neuroendocrine responses predisposing to or sheltering from stress-related diseases later in life. Epigenetic mechanisms are thought to mediate the effects of early social stress on the epigenome, and can give rise to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Early Childhood Education and Development
Share to Stress Responses and Cortisol

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22920182
DOI: 10.2217/epi.12.34

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Lasting Legacy of Social Stress on the Epigenome of the Hypothalamic–Pituitary–Adrenal AxisPMID 22920182Read ↗

Early Environments, Stress, and the Epigenetics of Human HealthSemantic proximity Read ↗

Epigenetic programming by early‐life stress: Evidence from human populationsSemantic proximity Read ↗

The epigenetics of perinatal stressSemantic proximity Read ↗

Biological embedding in mental health: an epigenomic perspective.Semantic proximity Read ↗

Perinatal stress and epigenetics.Semantic proximity Read ↗

Interactions of early-life stress with the genome and epigenome: from prenatal stress to psychiatric disordersSemantic proximity Read ↗

The Epigenetic Impacts of Social Stress: How does Social Adversity Become Biologically Embedded?Semantic proximity Read ↗

Biological Embedding of Early-Life Adversity and a Scoping Review of the Evidence for Intergenerational Epigenetic Transmission of Stress and Trauma in HumansSemantic proximity Read ↗

What’s in a name? The three genealogies of the social in social epigeneticsSemantic proximity Read ↗

Early-life adversity and long-term neurobehavioral outcomes: epigenome as a bridge?Semantic proximity Read ↗

Epigenetic Risk Factors in PTSD and DepressionSemantic proximity Read ↗

The social environment and the epigenome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.