Functional analyses in the silkworm, Bombyx mori, support a role for Notch signaling in appendage development but not the groucho-dependent pair-rule process.

Abstract excerpt

Pair-rule genes are crucial for generating dual segment periodicity for body plan patterning in Drosophila. Bombyx mori is an intermediate germband insect, in which the formation of posterior segments via sequential addition follows a different process from that in Drosophila, although it is somewhat comparable to the process that occurs in vertebrates. Notch signaling is involved in the segmentation of...

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