Article
EVER2 deficiency is associated with mild T-cell abnormalities.
Journal of clinical immunology - 1 Jan 2013
Crequer Amandine, Picard Capucine, Pedergnana Vincent, Lim Annick, Zhang Shen-Ying, Abel Laurent, Majewski Slawomir, Casanova Jean-Laurent, Jablonska Stefania, Orth Gerard, Jouanguy Emmanuelle
Abstract excerpt
Epidermodysplasia verruciformis (EV) is a rare genodermatosis characterized by persistent flat warts or pityriasis versicolor-like lesions caused by betapapillomaviruses (EV-HPVs). Autosomal recessive EVER1 and EVER2 deficiencies account for EV in most patients. The mechanisms by which mutations in these partners of the Zinc transporter ZnT1 impair host defense against EV-HPVs are still poorly understood....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.