Article
Peripheral blood T lymphocyte subsets in children with congenital asplenia.
Human immunology - 1 Nov 2012
Motkowski Radoslaw, Michalkiewicz Jacek, Mikoluc Bozena, Smolka-Afifi Dominika, Pietrucha Barbara, Kubiszewska Izabela, Piotrowska-Jastrzebska Janina, Bernatowska Ewa
Abstract excerpt
The aim of the current study was to examine whether a congenital lack of the spleen changes distribution, state of activation and function of peripheral lymphocyte T subsets. Seven children with congenital asplenia (CA) aged 1.5-17 years and seven age-matched controls were tested. By triple-color flow cytometry we examined: (1) the expression of CD3(+), CD4(+), CD8(+), CD19(+), and CD56(+) on lymphocytes; (2) the...
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