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Article

Differential regulation of cyclin B1 degradation between the first and second meiotic divisions of bovine oocytes.

Theriogenology - 1 Oct 2012

Liu W, Yin J, Zhao G, Yun Y, Wu S, Jones K T, Lei A

Abstract excerpt

During mammalian oocyte maturation, two consecutive meiotic divisions are required to form a haploid gamete. For each meiotic division, oocytes must transfer from metaphase to anaphase, but maturation promoting factor (cyclin-dependent kinase 1/cyclin B1) activity would keep the oocytes at metaphase. Therefore, inactivation of maturation promoting factor is needed to finish the transition and complete both these...

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Identifiers

PMID: 22901768
DOI: 10.1016/j.theriogenology.2012.06.006

Genes

CDK1

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