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Article

Bovine Immature Oocytes Acquire Developmental Competence During Meiotic Arrest In Vitro1

1 Jun 2002

Abstract excerpt

To test the hypothesis that oocytes require time to acquire developmental competence during meiotic arrest, we investigated the effects of butyrolactone I (BL I), a potent and specific inhibitor of cyclin-dependent kinase, on the developmental competence of bovine oocytes after in vitro fertilization (IVF) following release from meiotic arrest. In the present study, 4 culture conditions were used: addition of BSA...

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PMID: 12021049
DOI: 10.1095/biolreprod66.6.1696

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