Article
No association between the USP7 gene polymorphisms and colorectal cancer in the Chinese Han population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Li Xin, Wang Yang, Li Xing-Wang, Liu Bao-Cheng, Zhao Qing-Zhu, Li Wei-Dong, Chen Shi-Qing, Huang Xiao-Ye, Yang Feng-Ping, Wang Quan, Wang Jin-Fen, Xiao Yan-Zeng, Xu Yi-Feng, Feng Guo-Yin, Peng Zhi-Hai, He Lin, He Guang
Abstract excerpt
Colorectal cancer (CRC), now the third most common cancer across the world, is known to aggregate in families. USP7 is a very important protein with an important role in regulating the p53 pathway, which is critical for genomic stability and tumor suppression. We here genotyped eight SNPs within the USP7 gene and conducted a case-control study in 312 CRC patients and 270 healthy subjects in the Chinese Han...
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