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The Cryptic Competence Pathway in Streptococcus pyogenes Is Controlled by a Peptide Pheromone

22 Jun 2012

Abstract excerpt

Horizontal gene transfer is an important means of bacterial evolution that is facilitated by transduction, conjugation, and natural genetic transformation. Transformation occurs after bacterial cells enter a state of competence, where naked DNA is acquired from the extracellular environment. Induction of the competent state relies on signals that activate master regulators, causing the expression of genes...

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PMID: 22730123
DOI: 10.1128/jb.00830-12

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