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Article

Crystal structure of the globular domain of C1QTNF5: Implications for late-onset retinal macular degeneration.

Journal of structural biology - 1 Dec 2012

Tu Xiongying, Palczewski Krzysztof

Abstract excerpt

Autosomal dominant late-onset retinal macular degeneration (L-ORMD) is caused by a single S163R mutation in the C1q and tumor necrosis factor-related protein 5 (C1QTNF5) gene. The C1QTNF5 gene encodes a secreted and membrane-associated protein involved in adhesion of retinal pigmented epithelial...

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Identifiers

PMID: 22892318
DOI: 10.1016/j.jsb.2012.07.011
PMCID: PMC3496058

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22892318-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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