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Article

Biophysical characterisation of fibulin-5 proteins associated with disease.

Journal of molecular biology - 27 Aug 2010

Schneider Ralf, Jensen Sacha A, Whiteman Pat, McCullagh James S O, Redfield Christina, Handford Penny A

Abstract excerpt

FBLN5 encodes fibulin-5, an extracellular matrix calcium-binding glycoprotein that is essential for elastic fibre formation. FBLN5 mutations are associated with two distinct human diseases, age-related macular degeneration (AMD) and cutis laxa (CL), but the biochemical basis for the pathogenic ef...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20599547
DOI: 10.1016/j.jmb.2010.06.039

Genes

FBLN5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20599547-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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