Article
Immune safety of a novel oncolytic mutant M1 after administration in vivo.
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban - 1 Aug 2012
Jiang Lijun, Zhou Xiaoxi, Li Qinlu, Yu Fei, Huang Liang, Ma Quanfu, Zhou Jianfeng, Cao Yang
Abstract excerpt
The aim of this study was to evaluate the safety and efficiency of a novel, oncolytic adenovirus mutant M1 administered in conjunction with immunosuppressive agents. Animal models were established by administering purified M1 either intravenously or retroperitoneally. At different time points, bl...
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