Article
miR-210 has an antiapoptotic effect in pulmonary artery smooth muscle cells during hypoxia.
American journal of physiology. Lung cellular and molecular physiology - 15 Oct 2012
Gou Deming, Ramchandran Ramaswamy, Peng Xiao, Yao Lijun, Kang Kang, Sarkar Joy, Wang Zhixin, Zhou Guofei, Zhou Goufei, Raj J Usha
Abstract excerpt
MicroRNAs (miRNAs) were recently reported to play an important role in the pathogenesis of pulmonary arterial hypertension (PAH), but it is not clear which miRNAs are important or what pathways are involved in the process. Because hypoxia is an important stimulus for human pulmonary artery smooth muscle cell (HPASMC) proliferation and PAH, we performed miRNA microarray assays in hypoxia-treated and control...
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