Article
Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats.
PloS one - 1 Jan 2012
Zhang Xu, Zhao Yufeng, Zhang Menghui, Pang Xiaoyan, Xu Jia, Kang Chaoying, Li Meng, Zhang Chenhong, Zhang Zhiguo, Zhang Yifei, Li Xiaoying, Ning Guang, Zhao Liping
Abstract excerpt
Berberine, a major pharmacological component of the Chinese herb Coptis chinensis, which was originally used to treat bacterial diarrhea, has recently been demonstrated to be clinically effective in alleviating type 2 diabetes. In this study, we revealed that berberine effectively prevented the development of obesity and insulin resistance in high-fat diet (HFD)-fed rats, which showed decreased food intake....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.