Article
Granulocytes and vascularization regulate uterine bleeding and tissue remodeling in a mouse menstruation model.
PloS one - 1 Jan 2012
Menning Astrid, Walter Alexander, Rudolph Marion, Gashaw Isabella, Fritzemeier Karl-Heinrich, Roese Lars
Abstract excerpt
Menstruation-associated disorders negatively interfere with the quality of life of many women. However, mechanisms underlying pathogenesis of menstrual disorders remain poorly investigated up to date. Among others, this is based on a lack of appropriate pre-clinical animal models. We here employ a mouse menstruation model induced by priming mice with gonadal hormones and application of a physical stimulus into...
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