Article
Chest wall leiomyosarcoma after breast-conservative therapy for early-stage breast cancer in a young woman with Li-Fraumeni syndrome.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 Aug 2012
Henry Eve, Villalobos Victor, Million Lynn, Jensen Kristin C, West Robert, Ganjoo Kristen, Lebensohn Alexandra, Ford James M, Telli Melinda L
Abstract excerpt
Li-Fraumeni syndrome (LFS) is one of the most penetrant forms of familial cancer susceptibility syndromes, characterized by early age at tumor onset and a wide spectrum of malignant tumors. Identifying LFS in patients with cancer is clinically imperative because they have an increased sensitivity to ionizing radiation and are more likely to develop radiation-induced secondary malignancies. This case report...
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