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Article

Mutations in the CYP1B1 gene may contribute to juvenile-onset open-angle glaucoma.

Eye (London, England) - 1 Oct 2012

Su C-C, Liu Y-F, Li S-Y, Yang J-J, Yen Y-C

Abstract excerpt

PURPOSE: Glaucoma is one of the leading causes of blindness in the world. Juvenile-onset open-angle is a subtype of glaucoma. In this context, we investigate the possible mutations in the promoter and coding regions of the CYP1B1 gene among patients suffering juvenile-onset open-angle glaucoma (JOAG). METHODS: The CYP1B1 gene was analysed for mutations in 61 unrelated Taiwanese probands with JOAG and in 100...

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PMID: 22878448
DOI: 10.1038/eye.2012.159
PMCID: PMC3470042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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