Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

β-Cell Mass and Turnover in Humans

9 Aug 2012

Abstract excerpt

OBJECTIVE: We sought to establish β-cell mass, β-cell apoptosis, and β-cell replication in humans in response to obesity and advanced age. RESEARCH DESIGN AND METHODS: We examined human autopsy pancreas from 167 nondiabetic individuals 20-102 years of age. The effect of obesity on β-cell mass was examined in 53 lean and 61 obese subjects, and the effect of aging was examined in 106 lean subjects. RESULTS: β-Cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes and associated disorders
Share to Diabetes, Cardiovascular Risks, and Lipoproteins
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22875233
DOI: 10.2337/dc12-0421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

β-Cell Mass and Turnover in HumansPMID 22875233Read ↗

β‐cell mass in people with type 2 diabetesSemantic proximity Read ↗

Longevity of human islet α ‐ and β ‐cellsSemantic proximity Read ↗

The pancreatic β-cell in ageing: Implications in age-related diabetesSemantic proximity Read ↗

Human β-Cell Proliferation and Intracellular SignalingSemantic proximity Read ↗

Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implicationsSemantic proximity Read ↗

Linear correlation between beta-cell mass and body weight throughout the lifespan in Lewis rats: role of beta-cell hyperplasia and hypertrophy.Semantic proximity Read ↗

Maintenance of β-Cell Maturity and Plasticity in the Adult PancreasSemantic proximity Read ↗

β-Cell Replication Is the Primary Mechanism Subserving the Postnatal Expansion of β-Cell Mass in HumansSemantic proximity Read ↗

Greater organ involution in highly proliferative tissues associated with the early onset and acceleration of ageing in humansSemantic proximity Read ↗

Type 2 Diabetes-a Matter of ß-Cell Life and Death?Semantic proximity Read ↗

Genetic and biochemical pathways of β‐cell failure in type 2 diabetesSemantic proximity Read ↗

Biphasic changes in β-cell mass around parturition are accompanied by increased serotonin productionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.