Genetic Loci Associated with Platelet Traits and Platelet Disorders

doi:10.1055/s-0033-1334466

Article

Genetic Loci Associated with Platelet Traits and Platelet Disorders

6 Mar 2013

Abstract excerpt

Genetic investigations have led to important advances in our knowledge of genes, proteins, and microRNA that influence circulating platelet counts, platelet size, and function. The application of genome-wide association studies (GWAS) to platelet traits has identified multiple loci with a significant association to platelet number, size, and function in aggregation and granule secretion assays. Moreover, the...

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