Article
Elevated circulating osteoprotegerin and reduced matrix-metalloprotease-9 in post-menopausal women with chronic Hepatitis C virus infection.
Cytokine - 1 Nov 2012
Nanda Kavinderjit S, Brady Jennifer J, Murray Barbara F, Sullivan Owen, Fearon Ursula, McKenna Malachi J, Hegarty John E, O'Farrelly Cliona, Ryan Elizabeth J
Abstract excerpt
The failure of the immune response to clear the Hepatitis C virus (HCV) results in chronic inflammation that leads to liver cirrhosis. In general, women have a better prognosis than men and this may be associated with increased levels of anti-inflammatory mediators that are positively regulated by female sex hormones. Our aim was to determine if a cohort of Irish women who acquired infection through...
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