Article
Vitamin D supplementation improves serum markers associated with hepatic fibrogenesis in chronic hepatitis C patients: A randomized, double-blind, placebo-controlled study.
Scientific reports - 21 Aug 2017
Komolmit Piyawat, Kimtrakool Sayamon, Suksawatamnuay Sirinporn, Thanapirom Kessarin, Chattrasophon Kanita, Thaimai Panarat, Chirathaworn Chintana, Poovorawan Yong
Abstract excerpt
Hepatic fibrosis is the net accumulation of matrix tissue components which controlled by pro-fibrolytic enzymes, matrix metalloproteinases (MMPs), and pro-fibrotic cytokine, TGF-β1, and enzymes, tissue inhibitors of MMPs (TIMPs). Vitamin D (VD) supplementation has been shown to reverse these processes in vitro and in vivo. This study sought to determine the effect of VD supplementation on serum fibrotic markers...
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