Article
Association of Lis1 with outer arm dynein is modulated in response to alterations in flagellar motility.
Molecular biology of the cell - 1 Sept 2012
Rompolas Panteleimon, Patel-King Ramila S, King Stephen M
Abstract excerpt
The cytoplasmic dynein regulatory factor Lis1, which induces a persistent tight binding to microtubules and allows for transport of cargoes under high-load conditions, is also present in motile cilia/flagella. We observed that Lis1 levels in flagella of Chlamydomonas strains that exhibit defective motility due to mutation of various axonemal substructures were greatly enhanced compared with wild type; this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
