Article
Functional gene polymorphism of matrix metalloproteinase-1 is associated with benign hyperplasia of myo- and endometrium in the Russian population.
Genetic testing and molecular biomarkers - 1 Sept 2012
Morosova Elena B, Chukhlovin Alexei B, Kulagina Natalia V, Kipich Natalia V, Totolian Areg A
Abstract excerpt
AIMS: Estrogen-dependent hyperplasia of myo- and endometrium manifests as uterine leiomyoma or adenomyosis. We studied possible associations between common polymorphisms of matrix metalloproteinase (MMP) genes and clinical features of uterine hyperplasia. PATIENTS AND METHODS: One hundred seventy female patients with uterine leiomyoma (46.6±0.5 years) were observed. Clinical diagnosis was based on physical...
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