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Article

Hotspot oncomutations: implications for personalized cancer treatment.

Expert review of molecular diagnostics - 1 Jul 2012

Myers Meagan B, Wang Yiying, McKim Karen L, Parsons Barbara L

Abstract excerpt

Understanding the extent to which specific tumor mutations impact or mediate patient response to particular cancer therapies has become a rapidly increasing area of research. Recent research findings regarding four predominant mutational targets (KRAS, BRAF, EGFR and PIK3CA) show that these tumor...

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Source

Identifiers

PMID: 22845481
DOI: 10.1586/erm.12.51

Genes

BRAF
EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22845481-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Multiple Mutations within Individual Oncogenes: Examples and Clinical Implications.Semantic proximity Read ↗

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