Article
Dietary factors impact on the association between CTSS variants and obesity related traits.
PloS one - 1 Jan 2012
Hooton Henri, Angquist Lars, Holst Claus, Hager Jorg, Rousseau Francis, Hansen Rikke D, Tjønneland Anne, Roswall Nina, van der A Daphne L, Overvad Kim, Jakobsen Marianne Uhre, Boeing Heiner, Meidtner Karina, Palli Domenico, Masala Giovanna, Bouatia-Naji Nabila, Saris Wim H M, Feskens Edith J M, Wareham Nicolas J, Vimaleswaran Karani S, Langin Dominique, Loos Ruth J F, Sørensen Thorkild I A, Clément Karine
Abstract excerpt
BACKGROUND/AIMS: Cathepsin S, a protein coded by the CTSS gene, is implicated in adipose tissue biology--this protein enhances adipose tissue development. Our hypothesis is that common variants in CTSS play a role in body weight regulation and in the development of obesity and that these effects...
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