Article
TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders.
Translational psychiatry - 8 May 2012
Wirgenes K V, Sønderby I E, Haukvik U K, Mattingsdal M, Tesli M, Athanasiu L, Sundet K, Røssberg J I, Dale A M, Brown A A, Agartz I, Melle I, Djurovic S, Andreassen O A
Abstract excerpt
TCF4 is involved in neurodevelopment, and intergenic and intronic variants in or close to the TCF4 gene have been associated with susceptibility to schizophrenia. However, the functional role of TCF4 at the level of gene expression and relationship to severity of core psychotic phenotypes are not...
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