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Article

Neurotrophic gene polymorphisms and response to psychological therapy.

Translational psychiatry - 1 May 2012

Lester K J, Hudson J L, Tropeano M, Creswell C, Collier D A, Farmer A, Lyneham H J, Rapee R M, Eley T C

Abstract excerpt

Therapygenetics, the study of genetic determinants of response to psychological therapies, is in its infancy. Here, we investigate whether single-nucleotide polymorphisms in nerve growth factor (NGF) (rs6330) and brain-derived neutrotrophic factor (BDNF) (rs6265) genes predict the response to cognitive behaviour therapy (CBT). Neurotrophic genes represent plausible candidate genes: they are implicated in synaptic...

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Identifiers

PMID: 22832952
DOI: 10.1038/tp.2012.33
PMCID: PMC3365252

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BDNF
NGF

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