Article
A cryptic meprin-like proteolytic activity in mouse kidney brush border membranes.
The International journal of biochemistry - 1 Jan 1990
Macadam G C, Beynon R J, Bond J S
Abstract excerpt
1. Inbred mouse strains differ markedly in the expression of a kidney brush border metalloendopeptidase, meprin-a. 2. Brush border preparations from mice of the low-meprin-a phenotype (specific activities less than 5% of the high-meprin-a trait) contain a metallo-endopeptidase, meprin-b, that is larger than meprin-a, and which is inactive unless the membrane preparations are treated with trypsin. 3. This cryptic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
