Article
Deletion or underexpression of the Y-chromosome genes CDY2 and HSFY is associated with maturation arrest in American men with nonobstructive azoospermia.
Asian journal of andrology - 1 Sept 2012
Stahl Peter J, Mielnik Anna N, Barbieri Christopher E, Schlegel Peter N, Paduch Darius A
Abstract excerpt
Maturation arrest (MA) refers to failure of germ cell development leading to clinical nonobstructive azoospermia. Although the azoospermic factor (AZF) region of the human Y chromosome is clearly implicated in some cases, thus far very little is known about which individual Y-chromosome genes are important for complete male germ cell development. We sought to identify single genes on the Y chromosome that may be...
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