Confirmation of an ultrasound-induced mutation in two in-vitro mammalian cell lines.

doi:10.1016/0301-5629(90)90103-j

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Confirmation of an ultrasound-induced mutation in two in-vitro mammalian cell lines.

Ultrasound in medicine & biology - 1 Jan 1990

Doida Y, Miller M W, Cox C, Church C C

Abstract excerpt

In-vitro V79 and L5178Y cells were exposed in a rotating test tube to continuous-wave (CW) 1 MHz 35 W/cm2 ultrasound (0-4 or 0-3 min, respectively) and subsequently assayed for mutation as evidenced by resistance to 6-thioguanine (6-TG). There was a modest but statistically significant increase in mutation frequency in both cell types with increase in ultrasound exposure duration. X-ray exposures (3-9 Gy, a...

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Confirmation of an ultrasound-induced mutation in two in-vitro mammalian cell lines.

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