Article
Mutagenicity of ultrasound in cultured mammalian cells.
Ultrasound in medicine & biology - 1 Jan 2000
Kaufman G E
Abstract excerpt
Chinese hamster V79 cells were exposed in suspension to 1 MHz continuous wave ultrasound at spatial peak intensities of 7 and 35 W/cm2. Exposure durations were from 10 to 180 sec, so as to encompass the first decade of decreased survival at each intensity. Exposure at 35 W/cm2 resulted in the induction of 6-thioguanine-resistant mutants. The mutation frequency was approximately one-tenth that induced by x rays at...
Topics
- Animals
- Cell Line
- Cell Survival
- Cells, Cultured
- Cricetinae
- Drug Resistance
- Free Radicals
- Mutagenicity Tests
- Mutation
- Thioguanine
- Time Factors
- Ultrasonics