Article
Chronic inflammation and lung fibrosis: pleotropic syndromes but limited distinct phenotypes.
Mucosal immunology - 1 Sept 2012
Gifford A H, Matsuoka M, Ghoda L Y, Homer R J, Enelow R I
Abstract excerpt
Experimental models of lung fibrosis have been disappointing in predicting therapeutic responses to a wide variety of interventions in clinical fibrosing lung diseases. There are multiple potential reasons, but this fundamentally calls into question the validity of the models and their fidelity to clinical syndromes. We propose that the clinical diseases associated with pulmonary fibrosis, although manifesting a...
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