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Article

Genetic aspects of sodium channelopathy in small fiber neuropathy.

Clinical genetics - 1 Oct 2012

Hoeijmakers J G J, Merkies I S J, Gerrits M M, Waxman S G, Faber C G

Abstract excerpt

Small fiber neuropathy (SFN) is a disorder typically dominated by neuropathic pain and autonomic dysfunction, in which the thinly myelinated Aδ-fibers and unmyelinated C-fibers are selectively injured. The diagnosis SFN is based on a reduced intraepidermal nerve fiber density and/or abnormal thermal thresholds in quantitative sensory testing. The etiologies of SFN are diverse, although no apparent cause is...

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Identifiers

PMID: 22803682
DOI: 10.1111/j.1399-0004.2012.01937.x

Genes

SFN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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