Article
Small-fibre neuropathies--advances in diagnosis, pathophysiology and management.
Nature reviews. Neurology - 29 May 2012
Hoeijmakers Janneke G, Faber Catharina G, Lauria Giuseppe, Merkies Ingemar S, Waxman Stephen G
Abstract excerpt
Small-fibre neuropathy (SFN), a disorder of thinly myelinated Aδ-fibres and unmyelinated C-fibres, is clinically characterized by neuropathic pain symptoms and autonomic complaints. Diagnosis of SFN is challenging as the clinical picture can be difficult to interpret and results from nerve conduction studies are often normal. In cases of suspected SFN, measurement of intraepidermal nerve fibre density and/or...
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