Article
Redd1 is a novel marker of testis development but is not required for normal male reproduction.
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation - 1 Jan 2012
Notini A J, McClive P J, Meachem S J, van den Bergen J A, Western P S, Gustin S E, Harley V R, Koopman P, Sinclair A H
Abstract excerpt
In an effort to identify novel candidate genes involved in testis determination, we previously used suppression subtraction hybridisation PCR on male and female whole embryonic (12.0-12.5 days post coitum) mouse gonads. One gene to emerge from our screen was Redd1. In the current study, we demonstrate by whole-mount in situ hybridisation that Redd1 is differentially expressed in the developing mouse gonad at the...
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