Article
The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation.
PloS one - 1 Jan 2012
Krarup Nikolaj Thure, Grarup Niels, Banasik Karina, Friedrichsen Martin, Færch Kristine, Sandholt Camilla Helene, Jørgensen Torben, Poulsen Pernille, Witte Daniel Rinse, Vaag Allan, Sørensen Thorkild, Pedersen Oluf, Hansen Torben
Abstract excerpt
BACKGROUND AND AIM: Non-alcoholic fatty liver disease (NAFLD) is a common condition, associated with hepatic insulin resistance and the metabolic syndrome including hyperglycaemia and dyslipidemia. We aimed at studying the potential impact of the NAFLD-associated PNPLA3 rs738409 G-allele on NAFLD-related metabolic traits in hyperglycaemic individuals. METHODS: The rs738409 variant was genotyped in the...
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