Article
Analysis of HLA-DP in HLA-DR/GLO recombinant families and in the population of south-western France.
Tissue antigens - 1 Sept 1990
Thomsen M, Essaket S, Cambon-Thomsen A, Robbins F M, Hartzman R J, Arnaud J, Ohayon E
Abstract excerpt
The existing estimates of the recombination fraction between DR and DP are quite variable and often based on anecdotal observations. We have estimated the DR/DP crossover frequency on the basis of families typed for HLA markers and GLO. The frequency of DR/GLO crossing over was 8.7% (23/264 informative meioses), maternal recombinations being about twice as frequent as paternal ones. Of 17 DR/GLO recombinant...
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