QTL detection from regression analysis of 'generalized de-regressed proof' information.

Abstract excerpt

QTL detection using the regression of phenotypes on transmission probability is largely used when large families are available. In three generations designs, the use of a 'de-regressed proof' as a phenotype to be analysed was proposed by Weller et al. (1990) and Tribout et al. (2008). Our work generalizes this approach. A score (that we define as a 'generalized de-regressed proof') is described, which combines...

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