Article
Multiple quantitative trait loci mapping with cofactors and application of alternative variants of the false discovery rate in an enlarged granddaughter design.
Genetics - 1 Oct 2004
Bennewitz Jörn, Reinsch Norbert, Guiard Volker, Fritz Sebastien, Thomsen Hauke, Looft Christian, Kühn Christa, Schwerin Manfred, Weimann Christina, Erhardt Georg, Reinhardt Fritz, Reents Reinhard, Boichard Didier, Kalm Ernst
Abstract excerpt
The experimental power of a granddaughter design to detect quantitative trait loci (QTL) in dairy cattle is often limited by the availability of progeny-tested sires, by the ignoring of already identified QTL in the statistical analysis, and by the application of stringent experimentwise significance levels. This study describes an experiment that addressed these points. A large granddaughter design was set up...
Topics
- Animals
- Cattle
- Chromosome Mapping
- Computer Simulation
- Dairying
- False Positive Reactions
- Female
- Genetic Linkage
- Genetic Markers
- Genotype