Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumour suppressor genes in chemotherapeutic drug response.

Bioscience reports - 1 Aug 2012

Lai Dulcie, Visser-Grieve Stacy, Yang Xiaolong

Abstract excerpt

Since cancer is one of the leading causes of death worldwide, there is an urgent need to find better treatments. Currently, the use of chemotherapeutics remains the predominant option for cancer therapy. However, one of the major obstacles for successful cancer therapy using these chemotherapeuti...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Drug Resistance, Neoplasm
Share to PTEN gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to Molecular Targeted Therapy

Share to Mutation

Share to Neoplasms

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 22762204
DOI: 10.1042/BSR20110125
PMCID: PMC3392105

Genes

BRCA1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22762204-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumour suppressor genes in chemotherapeutic drug response.PMID 22762204Read ↗

The Different Mechanisms of Cancer Drug Resistance: A Brief ReviewSemantic proximity Read ↗

Drug resistance in human cancers - Mechanisms and implications.Semantic proximity Read ↗

Towards the overcoming of anticancer drug resistance mediated by p53 mutations.Semantic proximity Read ↗

Will therapies that target tumour suppressor genes be useful in cancer treatment?Semantic proximity Read ↗

Genomics and Cancer Drug ResistanceSemantic proximity Read ↗

Mechanisms of Drug Resistance in Ovarian Cancer and Associated Gene TargetsSemantic proximity Read ↗

Emerging Roles of SKP2 in Cancer Drug ResistanceSemantic proximity Read ↗

Genetic alterations in ovarian cancer cells that might account for sensitivity to chemotherapy in patients.Semantic proximity Read ↗

Deciphering the Molecular Mechanisms behind Drug Resistance in Ovarian Cancer to Unlock Efficient Treatment OptionsSemantic proximity Read ↗

p21 and p27: roles in carcinogenesis and drug resistanceSemantic proximity Read ↗

CKS1B as Drug Resistance-Inducing Gene—A Potential Target to Improve Cancer TherapySemantic proximity Read ↗

miR-92b-3p Regulates Cell Cycle and Apoptosis by Targeting CDKN1C, Thereby Affecting the Sensitivity of Colorectal Cancer Cells to Chemotherapeutic DrugsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.