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Article

Equation-free analysis of two-component system signalling model reveals the emergence of co-existing phenotypes in the absence of multistationarity.

PLoS computational biology - 1 Jan 2012

Hoyle Rebecca B, Avitabile Daniele, Kierzek Andrzej M

Abstract excerpt

Phenotypic differences of genetically identical cells under the same environmental conditions have been attributed to the inherent stochasticity of biochemical processes. Various mechanisms have been suggested, including the existence of alternative steady states in regulatory networks that are r...

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PMID: 22761552
DOI: 10.1371/journal.pcbi.1002396
PMCID: PMC3386199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22761552-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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