Article
Posttransplant recurrence of atypical hemolytic uremic syndrome.
Journal of nephrology - 1 Jan 2000
Valoti Elisabetta, Alberti Marta, Noris Marina
Abstract excerpt
Hemolytic uremic syndrome (HUS) is a rare disease characterized by microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. It is usually secondary to infections by strains of Escherichia coli (STEC) that produce Shiga-like toxin. In about 10% of patients, no STEC infections are reported. In these cases of atypical HUS (aHUS), mutations in genes encoding proteins of the complement system have...
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