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Article

GST polymorphisms and early-onset coronary artery disease in young South African Indians.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde - 8 May 2012

Phulukdaree Alisa, Khan Sajidah, Moodley Devapregasan, Chuturgoon Anil A

Abstract excerpt

BACKGROUND: Glutathione S-transferases (GSTs) detoxify environmental agents which influence the onset and progression of disease. Dysfunctional detoxification enzymes are responsible for prolonged exposure to reactive molecules and can contribute to endothelial damage, an underlying factor in coronary artery disease (CAD). OBJECTIVES: We aimed to assess 2 common polymorphic variant isoforms in GSTM1 and GSTP1 of...

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Source

Identifiers

PMID: 22748443
DOI: 10.7196/samj.5520

Genes

CAD
GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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