Article
The effect of input DNA copy number on genotype call and characterising SNP markers in the humpback whale genome using a nanofluidic array.
PloS one - 1 Jan 2012
Bhat Somanath, Polanowski Andrea M, Double Mike C, Jarman Simon N, Emslie Kerry R
Abstract excerpt
Recent advances in nanofluidic technologies have enabled the use of Integrated Fluidic Circuits (IFCs) for high-throughput Single Nucleotide Polymorphism (SNP) genotyping (GT). In this study, we implemented and validated a relatively low cost nanofluidic system for SNP-GT with and without Specific Target Amplification (STA). As proof of principle, we first validated the effect of input DNA copy number on genotype...
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