Article
Selective modulation of hepatic cytochrome P450 and flavin monooxygenase 3 expression during citrobacter rodentium infection in severe combined immune-deficient mice.
Drug metabolism and disposition: the biological fate of chemicals - 1 Oct 2012
Nyagode Beatrice A, Watkins William J, Kinloch Ryan D, Morgan Edward T
Abstract excerpt
The profile of selective modulation of hepatic cytochrome P450 (P450) gene expression caused by infection with the murine intestinal pathogen Citrobacter rodentium has been well characterized in multiple genetic backgrounds; yet, the mechanisms underlying this modulation are still not entirely understood. Although several studies have addressed the roles of cytokines from the innate immune system, the influence...
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