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Article

Predicting the activity of antimicrobial peptides with amino acid topological information.

Medicinal chemistry (Shariqah (United Arab Emirates)) - 1 Feb 2013

Shu Mao, Yu Rui, Zhang Yunru, Wang Juan, Yang Li, Wang Li, Lin Zhihua

Abstract excerpt

In this paper, VSTPV, was recruited as a novel set of structural and topological descriptors derived from principal component analysis (PCA) on 85 structural and topological variables of 166 coded and non-coded amino acids. By using partial least squares (PLS), we applied VSTPV for the study of quantitative structure-activity models (QSARs) studies on two peptide panels as 101 synthetic cationic Antimicrobial...

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PMID: 22741801
DOI: 10.2174/157340613804488350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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