Article
The lL-8 and IL-13 gene polymorphisms in inflammatory bowel disease and colorectal cancer.
DNA and cell biology - 1 Aug 2012
Walczak Anna, Przybylowska Karolina, Dziki Lukasz, Sygut Andrzej, Chojnacki Cezary, Chojnacki Jan, Dziki Adam, Majsterek Ireneusz
Abstract excerpt
Inflammatory bowel diseases (IBD) and colorectal cancer (CRC) are disorders that originate from immune disturbances. In our study, we evaluated the association between the -251 T/A interleukin (IL)-8 and the -1112 C/T IL-13 polymorphisms, the risk of IBD, and CRC development. Genotypes were determined by PCR-restriction fragment length polymorphism in 191 patients with CRC, 150 subjects with IBD, and 205 healthy...
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