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Effects of activation of AMPK on human breast cancer cell lines with different genetic backgrounds

21 Oct 2011

Abstract excerpt

Breast cancer remains a therapeutic challenge, and this has intensified the search for new drug targets. The AMP-activated protein kinase (AMPK) signalling pathway is emerging as having potential for intervention. We assessed the possible different effects of AMPK action on breast cancer cells by studying their impact on proliferation, apoptosis and the mitochondrial membrane potential in three breast cancer cell...

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PMID: 22740885
DOI: 10.3892/ol.2011.458

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